Dr. Romina R.M. Mizrahi
Division One: Brain and Therapeutics
CAMH - College Street Site
250 College Street
Toronto, ON M5T 1R8
Room: PET Centre
Dr. Mizrahi is an Associate Professor in Psychiatry at U of T, Clinical Scientist in the Research Imaging Centre at CAMH, a Full Member of the Institute of Medical Science (IMS) at U of T and a Full Graduate Faculty Member at the Pharmacology & Toxicology Department at U of T. She received her M.D. (1998) from the University of Buenos Aires and PhD (2007) from IMS. She has received funding from the Canadian Institutes of Health Research (CIHR) and the Ontario Mental Health Foundation (OMHF) to study dopamine using positron emission tomography (PET) in early psychosis and in those at risk for the disease. She also leads a new line of research to use a new F-18 radioligand to image neuroinflammation in-vivo and was in charge of translating this radioliand from the bench to the bedside at CAMH. This novel line of research received support of the Scottish Rite Charitable Foundation, the Alzheimer Society of Canada and the Brain & Behavior Research Foundation to carry out the first human experiments. Using this new radioligand, her lab is currently investigating neuroinflammation in schizophrenia, clinical high risk for psychosis, Alzheimer’s disease and mild cognitive impairment. Dr. Mizrahi has recently been awarded a $1.3 million grant from the National Institutes of Mental Health (NIMH) to follow up on her neuroinflammation work. Dr. Mizrahi has also just started the first human imaging studies of endocannabinoid metabolism in schizophrenia and clinical high risk for psychosis. This work has received initial pilot funding from the Brain & Behavior Research Foundation.
Dr. Mizrahi’s research focuses on developing a better understanding of how the brain functions in-vivo. Specifically, it focuses on the pathophysiology of the early course of schizophrenia and its treatment and those at high risk of developing psychosis. In pursuit of this goal her lab uses phenomenology, magnetic resonance imaging (MRI), and positron emission tomography (PET).