Our lab is interested in disease mechanisms in mental disorders like schizophrenia, depression and PTSD. We use animal models to investigate gene x environment interactions, epigenetics, transcription and neurodevelopment. We also have human clinical samples and studies probing spatial navigation in a VR environment.
Students have the opportunity to work on a number of related projects:
(1) miR137 gene mutant mouse models - characterization of behaviour, brain development, and molecular pathology related to schizophrenia;
(2) Clinical and molecular studies of new treatments for PTSD;
(3) Heritability of DNA methylation profiles and effects on behavioural phenotype in the mouse;
(4) Virtual reality tools for assessment and treatment in psychiatry.