Department of Psychiatry

The Toronto Dementia Research Alliance

Established by the Toronto Academic Health Science Network, the Toronto Dementia Research Alliance (TDRA) is an academic coalition between the five memory/dementia clinics affiliated with U of T:

  • Baycrest
  • CAMH
  • St. Michael’s Hospital
  • Sunnybrook Hospital
  • UHN
  • The Faculty of Medicine at U of T

The TDRA has fostered increased collaboration within these clinics, which has resulted in considerable increases in external funding to Division investigators.

The thematic highlights of Division collaborative projects include:

  • cognitive impairment in late life bipolar disorder, depression, and schizophrenia
  • depression and coronary artery disease, genetic and therapeutic studies in traumatic brain damage
  • imaging of brain inflammation as well as dopamine, serotonin and muscarinic receptors in a variety of late-life conditions and amyloid deposition in Alzheimer’s disease and frontotemporal dementia
  • pharmacotherapy of dementia and related psychiatric symptoms
  • psychotic depression
  • the relation between affective disorders and balance and mobility
  • neuroplasticity studies across the lifespan using brain stimulation techniques.

The Division is also undertaking a five year project funded by Brain Canada to conduct a randomized controlled trial to prevent Alzheimer’s dementia in older patients with depression or mild cognitive impairment. The project will be led by CAMH and includes all other four TDRA sites.